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Cheap Southeast Missouri hotels

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
The price is NZ$140 per night from 26 Dec to 27 Dec
NZ$140
includes taxes & fees
26 Dec - 27 Dec
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Motel 6 Poplar Bluff, MO
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Fully refundableReserve now, pay when you stay
The price is NZ$105 per night from 5 Jan to 6 Jan
NZ$105
includes taxes & fees
5 Jan - 6 Jan 2025
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Baymont Inn and Suites by Wyndham Farmington, MO
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 out of 5
3253 William Street, Cape Girardeau, MO
Fully refundable
The price is NZ$198 per night from 12 Jan to 13 Jan
NZ$198
includes taxes & fees
12 Jan - 13 Jan 2025
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
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La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

2.5 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Jackson. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is NZ$180 per night from 10 Jan to 11 Jan
NZ$180
includes taxes & fees
10 Jan - 11 Jan 2025
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is NZ$128 per night from 29 Dec to 30 Dec
NZ$128
includes taxes & fees
29 Dec - 30 Dec
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is NZ$229 per night from 7 Jan to 8 Jan
NZ$229
includes taxes & fees
7 Jan - 8 Jan 2025
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites Sikeston, MO
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is NZ$174 per night from 7 Jan to 8 Jan
NZ$174
includes taxes & fees
7 Jan - 8 Jan 2025
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Pear Tree Inn Sikeston
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Southeast Missouri

You’ve worked hard for your next holiday. You’ve earned it. Don’t sell yourself short by staying on an air mattress in a friend’s apartment, and don’t even think about pitching a tent. This city is jam-packed with accommodation so you’ll be able to retire to a comfortable bed after a day of exploring. Find deals on Southeast Missouri hotels and book a stay now.

Lay claim to your room like a miner would to his gold mine during your time spent at a Southeast Missouri hotels. Some might come with all the trimmings, like on-site spa service, workout facilities and a pool area. You’ll barely have to leave the grounds of the hotel. But if you do, you’ll be within walking distance of some major attractions. Explore the growing neighbourhoods outside the downtown area, or stay central and see what’s around the next corner. Head back to your hotel to utilise whatever amenities are available to you. You’ll feel like you never left home!

We want you to enjoy your time spent in this city without breaking the bank—even if you’re booking a trip last minute. Browse the lastminute.co.nz discount offers for great hotels in Southeast Missouri and save extra money so you can add some pizazz to your time away.

Southeast Missouri hotels essential information

Accommodation
531 hotels
Lowest Price
NZ$105
Highest Price
NZ$229
Popular hotels
Motel 6 Poplar Bluff, MO, Baymont Inn and Suites by Wyndham Farmington, MO, Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Drury Inn & Suites Cape Girardeau, Pear Tree Inn Cape Girardeau West, Drury Inn & Suites Sikeston, MO, Drury Plaza Hotel Cape Girardeau Conference Center, Pear Tree Inn Sikeston

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^Subject to availability and chosen travel dates.