I stayed at the Nile Valley Hotel for three nights.
It's located on the west bank, so it's closer to the Valley of the Kings/Queens/Nobles, but it's farther away from the majority of restaurants, the airport/train station, museums, Karnak, and Luxor Temple. However, the ferry port is just a short walk away from the hotel and getting across the Nile is cheap and easy.
The staff was friendly and the room amenities/cleanliness was decent, about what you'd expect for the price.
Overall, I was happy with my stay at the Nile Valley Hotel.