Uno Mediterraneo offers peaceful accommodations adjacent to the busier parts of Milan - within walking distance (no more than 30 minutes) and easy public transportation access (10 minutes) to the heart of Milan: Duomo, Brera, and more.
We stayed at the Uno on business trips, as well as on personal trips, visiting family and friends. We used the room as our base camp, and occasionally consumed the delicious breakfast offerings. The lobby area is not a hip place to attend or be seen at, but rather a comfortable space to sit and work in peace while you sip your coffee.
The facility is clean, well organized, with all amenities expected for a city break or a short business trip. The rooms are sizable compared to the typical European standards, clean, basic (but plentiful) and airy. The staff are no-nonsense, welcoming, pleasant and very friendly - Italian ;)
We have stayed in ArBnBs for longer stays, and in various hotels in Milan for 203 day stays. The Uno is perfect in terms of value received for the price. Unless you want the dolce vita, or unless you need to stay specifically in another part of Milan, the Uno is your best choice for a 2-3 day stay, whatever the reason.