Book Holiday Homes in Port Saint Lucie

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Port Saint Lucie

Sheraton PGA Vacation Resort, Port St. Lucie

Sheraton PGA Vacation Resort, Port St. Lucie

3.5 out of 5
8702 Champions Way, Port Saint Lucie, FL
Fully refundableReserve now, pay when you stay
The price is NZ$506 per night from 25 Mar to 26 Mar
NZ$506
includes taxes & fees
25 Mar - 26 Mar
Stay at this 3.5-star eco-certified vacation home in Port Saint Lucie. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the ...
Sheraton PGA Vacation Resort, Port St. Lucie
Cozy Oasis

Cozy Oasis

Port St. Lucie
The price is NZ$542 per night from 25 Mar to 26 Mar
NZ$542
includes taxes & fees
25 Mar - 26 Mar
Book a stay at this family-friendly vacation home in Port Saint Lucie. Enjoy free WiFi, private pools, and an in-room coffeemaker. Popular attractions Port St. ...
Cozy Oasis
Easy access from I95 and Turnpike, beautiful lake view and 25 min from the beach

Easy access from I95 and Turnpike, beautiful lake view and 25 min from the beach

Port St. Lucie
Stay at this vacation home in Port Saint Lucie. Enjoy free WiFi, cable/satellite TV service, and an in-room coffeemaker. Popular attractions Woodlands Trails ...
Easy access from I95 and Turnpike, beautiful lake view and 25 min from the beach
Save an average of 15% on thousands of hotels when you're signed in
Port St Lucie Vacation Rental w/ Furnished Patio!

Port St Lucie Vacation Rental w/ Furnished Patio!

Port St. Lucie
Stay at this vacation home in Port Saint Lucie. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions Spruce Bluff Preserve and Port ...
Port St Lucie Vacation Rental w/ Furnished Patio!
Paradise in Port Saint Lucie

Paradise in Port Saint Lucie

Port St. Lucie
Book a stay at this family-friendly vacation home in Port Saint Lucie. Enjoy balconies, cable/satellite TV service, and an in-room coffeemaker. Popular attractions ...
Paradise in Port Saint Lucie
Private Heated Pool, Tropical Breezes from the Ocean, Only 10 Minutes to Beach!

Private Heated Pool, Tropical Breezes from the Ocean, Only 10 Minutes to Beach!

Port St Lucie
Stay at this vacation home in Port Saint Lucie. Enjoy free WiFi, private pools, and a water park. Popular attractions Savannas Preserve State Park and Walton ...
Private Heated Pool, Tropical Breezes from the Ocean, Only 10 Minutes to Beach!
The Flamingo Casa

The Flamingo Casa

Port St. Lucie
Stay at this vacation home in Port Saint Lucie. Enjoy free WiFi, a garden, and patios. Popular attractions Port St. Lucie Botanical Gardens and Spruce Bluff ...
The Flamingo Casa
Waterfront Home, Private Dock; 3 miles to Tradition Town Center

Waterfront Home, Private Dock; 3 miles to Tradition Town Center

Port St. Lucie
Stay at this vacation home in Port Saint Lucie. Enjoy patios, cable/satellite TV service, and an in-room coffeemaker. Popular attractions PGA Center for Golf ...
Waterfront Home, Private Dock; 3 miles to Tradition Town Center
Lush | Tropical | Modern Home w/ Heated Pool & Spa

Lush | Tropical | Modern Home w/ Heated Pool & Spa

Port St Lucie
Book a stay at this family-friendly vacation home in Port Saint Lucie. Enjoy free WiFi, private pools, and a garden. Popular attractions Savannas Preserve State ...
Lush | Tropical | Modern Home w/ Heated Pool & Spa
Don't see what you're looking for?
See all available properties in Port Saint Lucie
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Port Saint Lucie Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Port Saint Lucie vacation homes are the perfect way for you to wing it.

Holiday houses in Port Saint Lucie let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Port Saint Lucie in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Port Saint Lucie adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Port Saint Lucie with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Port Saint Lucie vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Port Saint Lucie Holiday Homes essential information

Accommodation
274 Holiday Homes
Lowest Price
NZ$219
Highest Price
NZ$542
Popular accommodation
Sheraton PGA Vacation Resort, Port St. Lucie, Cozy Oasis, Easy access from I95 and Turnpike, beautiful lake view and 25 min from the beach, Port St Lucie Vacation Rental w/ Furnished Patio!, Paradise in Port Saint Lucie, Private Heated Pool, Tropical Breezes from the Ocean, Only 10 Minutes to Beach!, The Flamingo Casa, Waterfront Home, Private Dock; 3 miles to Tradition Town Center, Lush | Tropical | Modern Home w/ Heated Pool & Spa

Top trending hotels in Port Saint Lucie

Best Western Port St. Lucie

Best Western Port St. Lucie

2.5 out of 5
7900 S US Highway 1, Port Saint Lucie, FL
Fully refundableReserve now, pay when you stay
The price is NZ$239 per night from 31 Mar to 1 Apr
NZ$239
includes taxes & fees
31 Mar - 1 Apr
Book a stay at this business-friendly hotel in Port Saint Lucie. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Best Western Port St. Lucie
SpringHill Suites Port St. Lucie

SpringHill Suites Port St. Lucie

3 out of 5
2000 NW Courtyard Cir, Port Saint Lucie, FL
Fully refundableReserve now, pay when you stay
The price is NZ$267 per night from 30 Mar to 31 Mar
NZ$267
includes taxes & fees
30 Mar - 31 Mar
Stay at this 3-star golf hotel in Port Saint Lucie. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
SpringHill Suites Port St. Lucie
Hampton Inn & Suites Port St. Lucie, West

Hampton Inn & Suites Port St. Lucie, West

2.5 out of 5
155 SW Peacock Blvd, Port Saint Lucie, FL
Fully refundableReserve now, pay when you stay
The price is NZ$343 per night from 30 Mar to 31 Mar
NZ$343
includes taxes & fees
30 Mar - 31 Mar
Book a stay at this business-friendly hotel in Port Saint Lucie. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hampton Inn & Suites Port St. Lucie, West
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Port St. Lucie, an IHG Hotel

Holiday Inn Port St. Lucie, an IHG Hotel

3 out of 5
10120 S Federal Hwy, Port Saint Lucie, FL
Fully refundable
The price is NZ$219 per night from 31 Mar to 1 Apr
NZ$219
includes taxes & fees
31 Mar - 1 Apr
Stay at this 3-star business-friendly hotel in Port Saint Lucie. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
Holiday Inn Port St. Lucie, an IHG Hotel
Don't see what you're looking for?
See all available properties in Port Saint Lucie
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.