Book Santee hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Santee

Cheap Santee hotels

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
The price is NZ$151 per night from 5 Dec to 6 Dec
NZ$151
includes taxes & fees
5 Dec - 6 Dec
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Baymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
The price is NZ$245 per night from 1 Dec to 2 Dec
NZ$245
includes taxes & fees
1 Dec - 2 Dec
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
The price is NZ$272 per night from 5 Dec to 6 Dec
NZ$272
includes taxes & fees
5 Dec - 6 Dec
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Hampton Inn Santee-I-95
Save an average of 15% on thousands of hotels when you're signed in
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Fully refundableReserve now, pay when you stay
The price is NZ$208 per night from 5 Dec to 6 Dec
NZ$208
includes taxes & fees
5 Dec - 6 Dec
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Tru By Hilton Santee
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway, Santee, SC
Fully refundableReserve now, pay when you stay
The price is NZ$113 per night from 5 Dec to 6 Dec
NZ$113
includes taxes & fees
5 Dec - 6 Dec
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Quality Inn & Suites
Holiday Inn Santee, an IHG Hotel

Holiday Inn Santee, an IHG Hotel

3 out of 5
139 Bradford Blvd, Santee, SC
Fully refundable
The price is NZ$218 per night from 5 Dec to 6 Dec
NZ$218
includes taxes & fees
5 Dec - 6 Dec
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Holiday Inn Santee, an IHG Hotel
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
Fully refundableReserve now, pay when you stay
The price is NZ$189 per night from 5 Dec to 6 Dec
NZ$189
includes taxes & fees
5 Dec - 6 Dec
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
Comfort Inn & Suites Santee
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98, Santee, SC
Fully refundableReserve now, pay when you stay
The price is NZ$217 per night from 5 Dec to 6 Dec
NZ$217
includes taxes & fees
5 Dec - 6 Dec
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Best Western Plus Santee Inn
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
The price is NZ$113 per night from 1 Dec to 2 Dec
NZ$113
includes taxes & fees
1 Dec - 2 Dec
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Travelodge by Wyndham Santee
Don't see what you're looking for?
See all available properties in Santee
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Santee

About to take off and visit Orangeburg? Keen to book a bed in Santee? Currently, we have 11 places to base yourself within a 10-kilometre distance of the main part of Santee.

Stay close to the heart of Santee. Accommodations here include the Holiday Inn Santee and Hampton Inn Santee I-95.

Outlaying less on your hotel often means more dough for fun. Why not check out the Super 8 Santee, Red Roof Inn Santee and Rodeway Inn?

35 kilometres away from the middle of Santee is the Hampton Inn Manning. Alternatively, the Comfort Inn & Suites Santee is located 2 kilometres away. If you'd prefer, you could make a booking at the Best Western Plus Santee Inn or the Quality Inn And Suites.

Looking to travel further afield? You're in luck! South Carolina Midlands has many other attractions to keep you busy throughout your stay. If you're a nature lover, you won't want to miss South Carolina Midlands's rolling hills. If nature's not your thing, head to the area's historic mansions and gardens. Or join the locals hiking, zip-lining and horse riding while you are here.

You will find various accommodation options in Stilton, situated 35 kilometres to the west of Santee. The Comfort Inn & Suites and Holiday Inn Express Hotel & Suites Orangeburg are some of the hotels here.

Just because you are travelling, doesn't mean you can't enjoy your obsession for sports. Colonial Life Arena can be found 80 kilometres to the northwest of Santee. The Sheraton Columbia Downtown Hotel and the Hilton Columbia Center are good options if you hope to get amongst it.

Charleston International Airport can be found 75 kilometres away from the centre of Santee. Should you wish to stay nearby, you can easily secure a room at the Embassy Suites North Charleston - Airport/Hotel & Convention or the Residence Inn Charleston Airport.

Santee hotels essential information

Accommodation
235 hotels
Lowest Price
NZ$113
Highest Price
NZ$272
Popular hotels
Baymont by Wyndham Santee, Fairfield Inn & Suites by Marriott Santee, Hampton Inn Santee-I-95, Tru By Hilton Santee, Quality Inn & Suites, Holiday Inn Santee, an IHG Hotel, Comfort Inn & Suites Santee, Best Western Plus Santee Inn, Travelodge by Wyndham Santee

Most recent Santee hotel reviews

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.