All Hotels In Southwest Illinois, Illinois
There are 646 hotels in Southwest Illinois
- Drury Inn & Suites Sikeston, MO
- Holiday Inn Express & Suites St. Louis West - Fenton by IHG
- Hampton Inn & Suites St. Louis/Alton
- Drury Inn & Suites St. Louis Arnold
- Courtyard by Marriott St. Louis West County
- SpringHill Suites by Marriott St. Louis Airport/Earth City
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Fairfield Inn & Suites St Louis Westport
- Candlewood Suites Cape Girardeau by IHG
- Harrah's Metropolis Hotel & Casino
- Staybridge Suites St Louis - Westport by IHG
- Hampton Inn & Suites St. Louis/South I-55
- Holiday Inn Express Metropolis by IHG
- Comfort Inn Festus - St Louis South
- Sheraton Westport Plaza Hotel St. Louis
- Holiday Inn Express & Suites Perryville by IHG
- Quality Inn
- The Lodge at Grant's Trail
- Sonesta Simply Suites St Louis Earth City
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Jackson MO
- The Last Hotel
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Days Inn and Suites by Wyndham Sikeston
- Extended Stay America Select Suites St Louis Westport Craig
- Super 8 by Wyndham Staunton
- Sheraton Westport Chalet Hotel St. Louis
- Hampton Inn Cape Girardeau I 55 East
- Town House Inn Cape Giradreau
- Comfort Suites Jackson-Cape Girardeau
- Americas Best Value Inn St. Louis Downtown
- Baymont by Wyndham Litchfield
- Extended Stay America Select Suites St Louis Earth City
- Super 8 by Wyndham Metropolis
- Homewood Suites by Hilton St. Louis Westport
- Residence Inn by Marriott St. Louis West County
- Super 8 by Wyndham Harrisburg
- MainStay Suites St Louis Airport
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Hampton Inn by Hilton Litchfield
- Residence Inn by Marriott St Louis Airport
- Cobblestone Inn & Suites - Altamont
- Holiday Inn Express & Suites Litchfield West by IHG
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- WoodSpring Suites St. Louis Arnold
- Fairfield Inn & Suites by Marriott St. Louis South
- Microtel Inn & Suites by Wyndham Sainte Genevieve
- Welcome Suites Hazelwood
- Hampton Inn St. Louis Southwest
- Comfort Inn Alton near I-255
- Days Inn by Wyndham Perryville
- Benton Park Inn
- Motel 6 Metropolis, IL
- Quality Inn Litchfield Route 66
- Silo Farm Haus- located in the heart of wine country!
- Comfort Inn & Suites Sikeston I-55
- Hotel 7 Vienna
- Super 8 by Wyndham Alton
- Super 8 by Wyndham Charleston/Sikeston East MO
- OYO Hotel St. Louis Downtown City Center MO
- Quality Inn Charleston - Sikeston
- Quality Inn Perryville I-55
- Residence Inn St Louis Westport
- Quality Inn
- Central West End B&B
- Motel 6 Litchfield, IL
- Super 8 by Wyndham Sikeston/Miner Area
- Indoor Heated Pool pontoon boat fish 3 full baths sleeps 17 in beds 2025 SALE!!!
- Super 8 by Wyndham Jerseyville
- Grand Center Inn
- Baymont by Wyndham Metropolis
- Super 8 by Wyndham Pevely
- Carlin Villa Motel
- Eagle Inn Charleston
- St. Louis Airport Hotel